Long Non-coding RNAs Conduct a Synaptic Symphony to Orchestrate Fear Extinction MemoryDecember 12, 2023Most epigenetic studies are music to our ears, but do you prefer “The Rolling Histones,” “Run-5mC,” or something more classical while working in the lab? Well, move over rock and hip-hop, as an epigenetic masterpiece now describes how a long non-coding RNAs (lncRNA) epigenetically conducts a synaptic symphony to “orchestrate” fear extinction memory. Previous pleasant-sounding […]
DNA Methylation Analysis Shows How Cannabis Exposure Increases the Risk of Adverse Health OutcomesDecember 11, 2023Do not risk missing a new paper describing a recent trans-ancestry epigenome-wide association study (EWAS) highlighting the significant health risks of recreational cannabis! In a fascinating new study, researchers now reveal that cannabis exposure can impact DNA methylation levels at specific regions independent of cigarette smoking to increase the risk of adverse health outcomes. Risk-averse […]
Messing Up Methylation: Formaldehyde is a Targeted Bull in a China Shop November 27, 2023Just like a bull in a china shop, formaldehyde (FA) was thought to damage almost everything it bumped into. But new research shows that it’s a lot more targeted, and it really likes proteins involved in DNA methylation. Sure, FA can preserve brains in jars, but it’s most often used in consumer products like glues and […]
A Super-specific Epigenetic Editing Strategy Silences Disease-associated Dominant MutationsNovember 22, 2023Is it a bird? Is it a plane? No, it’s a “super” new study that combines the strength, ability, and ingenuity of epigenetic editing to shut down our nemesis – the disease-associated dominant mutation – while leaving the innocent bystander allele unharmed! Epigenetic superheroes led by Albert Jeltsch (University of Stuttgart) aimed to battle their […]
The Brain Cell Census: A Deeper Epigenomic Understanding of the Mammalian MainframeNovember 13, 2023If you have epigenetics on the brain like us, concentrate your mammalian mainframe on the recently published marvels on the brain’s epigenome from the NIH’s Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative – Cell Census Network (BICCN). Recent work brought together under the guise of the Brain Cell Census now reports on the examination […]
