NIH Digs into the Diet Movement with New Epigenetics Research GrantsJuly 16, 2009Nowadays it seems like everybody’s on some kind of a diet. Until recently, even public funding for epigenetic research had been leaner than a movie star on the South Beach diet. But with last year’s funding of the Roadmap Initiative and yesterday’s release of grant applications for the study of diet and epigenetics, things are […]
On Your Marks: Antibodies That Should be in Every Epigenetics Researcher’s FridgeJuly 15, 2009Chromatin is a complicated scene. Staying on top of who’s who in residue and degree-specific histone modifications and chromatin modifying proteins is more than a full time job. So, if you’re looking to jump start your investigations and pull down some quick hitting data, you’ll want to consider picking up on some quality antibodies targeting […]
This Hi-Def Methylation Experience is Brought to You by Bisulfite CaptureJuly 15, 2009Even if you don’t have a new flat screen HD TV hanging in your living room, most of us have at least seen the beauty that is HD when strolling through the TV section in the local Wal-Mart or Best Buy. The picture is so crystal-clear that watching a game in HD is just like […]
miBridge: Bringing mRNA UTRs TogetherJuly 9, 2009When it comes to the the miRNA translational repression model, 5’ UTRs have been neglected more than California’s budget deficit in recent years. Despite computational approaches predicting oodles of miRNA docking sites for miRNAs in the 5’ UTR, we haven’t seen that many studies tackle the other side of miRNA repression. But just a few […]
Differentiation Got Your Chromatin in a Bind?July 8, 2009Euchromatin could be what gives stem cells their stemness. A screen for factors that both reduce embryonic stem (ES) cells’ ability to expand and diminish their expression of stem cell marker Oct4 yielded just one that hadn’t been seen before: the chromatin-remodeling enzyme Chd1. Chd1 recognizes di-or tri-methylated histone 3 at lysine 4 (H3K4me2/3) – […]
