NanoNOMe Combines Nanopore and NOMe-seq to Mine the Allele-specific EpigenomeJanuary 18, 2021Gnomes are small magical creatures that mine for treasures, so you might wonder if a nanoNOMe is an even tinier being. Well actually it’s a new molecular technique, but its applications are nothing short of magical. Several methods have been developed to probe DNA methylation, transcription factors, and chromatin state simultaneously. Many are based on […]
DNA Methylation Can Take You to Higher Ground!January 16, 2021It’s not often that an epigenetics study can elevate you to a higher plane, but uplifting new research into those who live at the top of the world now establishes that DNA methylation profiles can take you higher and higher and support high-altitude living. Researchers led by Ainash Childebayeva (Max Planck Institute for the Study […]
Are My Eggs Getting Old? Single-cell Multiomics Shows that Oocytes Have an Epigenetic TimestampJanuary 13, 2021Unfortunately, real life is not a fairy tale. Unlike Sleeping Beauty, sleeping oocytes are not frozen in time. As oocytes get older, they acquire epigenetic changes that make it harder for them to get on with their baby making business. Important new single-cell multiomics work from Gavin Kelsey’s and Myriam Hemberger’s teams at the Babraham Institute shows […]
The Epigenetic Clock – From Deep Space to Deep LearningDecember 30, 2020As the year comes to its end, our epigenetic clocks keep on ticking, and hot new DNA methylation-based studies keep rolling in. Here, we gaze into two deeply interesting studies that take us on an epigenetic journey from deep space to deep learning by reporting how space travel can influence epigenetic aging and how neural […]
DNA Methylation Contributes to the Chaos and Complications of COVID-19December 14, 2020While the cough was the cardinal consideration, COVID-19 has been causing chaos in every organ system, including lungs, heart, brain, blood, liver, and skin. In fact, the involvement of these non-lung systems predicts increased mortality and new research now shows that DNA methylation is a contributor to COVID-19. Researchers from the laboratory of Arjun Deb […]
