NOMe-seq Goes Genome WideSeptember 19, 2012NOME-seq (Nucleosome Occupancy and Methylome Sequencing) made a big splash when it was introduced just over a year ago because of its novel ability to profile nucleosome positions and DNA methylation at the same time, on a single DNA strand. Now researchers from the University of Southern California Epigenome Center have powered-up the technique by […]
From A to G: The Ins and Outs of ChIP BeadsSeptember 12, 2012If you don’t run chromatin immunoprecipitation (ChIP) experiments on a daily basis, there’s a good chance that you find the dizzying variety of available immunoprecipitation bead choices a little overwhelming. We asked the ChIP experts from EMD Millipore to help us break down what you need to know about ChIP beads so that you choose […]
DNA Methylation Runs the Genomic DefenseSeptember 12, 2012Novel research findings over the last last five years have introduced more exceptions than rules in the field of DNA methylation in gene silencing. Whether DNA methylation stars as the cause or effect in the thickening regulatory plot continues to be discussed in labs around the world. A British team of researchers led by Dr. […]
EpiGenie Reviews Non-Coding RNAs and Epigenetic Regulation of Gene ExpressionSeptember 11, 2012In recent years, studies exploring the modulation of gene transcription by non-coding RNAs have definitely been on the rise. This book, Non-Coding RNAs and Epigenetic Regulation of Gene Expression, written by a selection of highly regarded scientists, and edited by Kevin Morris, represents an overview and summary of this important new field to date. It’s […]
Predicting Gene Expression with Chromatin FeaturesSeptember 11, 2012As any weather forecaster can tell you, making accurate predictions is tough. But researchers now report that they’ve confirmed the power of chromatin features to predict gene expression. They’ve also come up with some new insights, too. Sure, some histone mods are associated with transcriptional repression, whereas others typically mark active spots. But many studies […]
