Keeping Up with the TET Enzyme Family and DNA DemethylationJuly 9, 2014That wacky TET enzyme family is at again, but rather than being caught in some compromising positions with DNA or cheating on Cytosine; this time our favorite enzyme family is slacking off, or as they call it ‘working smart’ and splitting up important active DNA demethylation work. Researchers at the Mayo Clinic provide novel insight into how the TET […]
Targeted Chromatin Capture (T2C)July 7, 2014With great resolution comes great price and manpower requirements, so the demand for a happy medium has remained at large for all those trying to catch some chromatin conformation. New players like Capture-C have stepped up to the plate and now Researchers from the Erasmus University Medical Center (The Netherlands) announce T2C: Targeted Chromatin Capture. Chromosome conformation capture […]
Placental Biomarker Captures Maternal StressJune 30, 2014Stress has a funny way of sneaking up on you, and with the newly understood dangers of stress being transmitted across generations, keeping the drama to a minimum is huge concern for expecting mothers. So, wouldn’t it be nice to have some sort of an early stress warning device? Placental miRNAs have already been used to […]
Going Global with DNA Methylation AnalysisJune 24, 2014It’s human nature to get enthralled by the latest, shiny new technology on the market, but sometimes a more established approach is just as effective. We recently connected with our friends at Zymo Research who point out that for DNA methylation analysis, researchers may not always need all of NGS’s bells and whistles, especially when […]
An Introduction to Epigenetic Editing with Dr. Marianne RotsJune 23, 2014Dr. Marianne Rots, Professor of Molecular Epigenetics and Head of Epigenetic Editing Laboratory at University of Groningen, Netherlands provides an informative overview of the current state of epigenetic editing approaches. Intro to Epigenetic Editing Epigenetic editing exploits the two main characteristics of epigenetics. On the one hand, epigenetic marks are heritable. This means the epigenetic […]
