A Suite of New Tools to Solve Single-cell Epigenetic EnigmasDecember 23, 2021Welcome explorers of the epigenome! Are you looking for new tools to help answer the toughest of epigenetic enigmas? Then check out this suite of single-cell methods papers from technologically-talented teams led by Aviv Regev (Broad Institute of MIT and Harvard) and collaborators. inCITE into How Transcription Factors Shape In Vivo Gene Expression A collaboration […]
A Youthful Brain Boost via DNA Hydroxymethylation: TET1 Enters the Myelin Repair Technician’s ToolkitDecember 13, 2021Does it feel like your aging brain cells have been firing a little slower lately? Why not refresh your connection and speed up your synaptic signal transmission with a visit from your oligodendrocyte myelin repair technicians. Their youthful TET1 and DNA hydroxymethylation repair kit will bring you back to fiber-optic speeds in no time. This […]
A Circulating microRNA Makes a Macro Difference in the Battle Against COVID-19November 28, 2021From holding the door open to passing on a link to an exciting epigenetics paper – small gestures can make an enormous difference to anyone’s day! Now, an exciting new study suggests that the expression of a microRNA has a macro impact during SARS-CoV-2 infection and could represent an important target for the treatment of […]
Automated Chromatin Profiling Platforms Autopilot Patients to the ClinicNovember 22, 2021From human-free supermarket check-outs to autopiloted cars, the modern world is rapidly moving towards automation. In the most recent advance, a rabble of robotic researchers has applied related technological tricks to epigenetic assays to “autopilot” high-throughput chromatin profiling and provide a clinical tool that may support optimized treatment choices in leukemia patients. Specifically, a technology-driven […]
dCas9 Hinders DNA Methylation to Cast Off the Confounds from CausalityNovember 4, 2021Our day-to-day experiences provide a clear understanding of cause-and-effect; a lab mate’s birthday means cake for lunch, and cake for lunch means hours of hard work in the gym! While this cake-centric concept might be simple and easy to follow, the seemingly straightforward causal relationship between DNA demethylation and the upregulation of gene expression, much […]
