CpG Island (R)EvolutionJune 2, 2011CpG islands and their methylation patterns are the epigeneticists bread and butter, and it’s been assumed by many that there are evolutionary reasons behind their existence. New data suggests that not all CpG islands were created equal, and much like Donald Trump’s hair, can’t entirely be explained by natural selection. High-powered researchers from the Weizmann […]
Posttraumatic Stress Risk Altered by DNA MethylationJune 1, 2011After nearly a decade of sending troops into harms way, the U.S. is now coping with the aftermath that those situations can create for our armed forces, like posttraumatic stress disorder (PTSD). So it’s nice to see progress made towards understanding that condition. While many people are exposed to traumatic events, only a fraction will develop […]
EpiGenie 5-hmC Round-upJune 1, 2011We’re not entirely sure what the enigmatic base variant 5-hydroxymethylcytosine (5-hmC) does or why it’s important yet, but we do know it’s become one of our favorite epigenetic topics. Whether you’re a 5-hmC newbie, or just need a quick refresher, you’ll want to check out our favorite articles we’ve featured on the subject. Hydroxymethylcytosine Shakes […]
Histone Tails Take the Lead In De Novo MethylationMay 29, 2011“Newborn” (or de novo) DNA sequences come into this world just like newborn human babies—naked. So, how do new sequences get their DNA methylation on? Researchers from the Chinese Academy of Sciences say they’ve figured out what happens after the histones settle in: H3 tails that lack methylation at K4 bind to and activate de […]
Become a Methyl-Detective Using QIAGEN’s EpiTect Plus Bisulfite KitsMay 19, 2011Bisulfite conversion is still the gold-standard method used to investigate DNA methylation, but that doesn’t mean it’s easy. When you’re trying to solve the mystery of methylation in your favorite samples, you want tools that will get you to the right answer, right away. QIAGEN’s EpiTect Plus Bisulfite Kits takes you all the way from […]
