No Cells? No Problem! How Cell-Free DNA Methylation Profiles May Guide Cancer ManagementAugust 20, 2022When set the monumental task of studying how the epigenetic mechanisms underlying tumorigenesis, isolating a cell sample usually represents your first analytical port of call; however, research now suggests that liquid biopsies of a patient’s blood may provide a wealth of information from cell-free DNA. Furthermore, widening this approach to DNA methylation analysis may also […]
The Human Imprintome Maps out the Epigenetic Roots of DiseaseAugust 20, 2022A well-illustrated map may have helped the Spanish easily locate El Dorado or David Livingstone pinpoint the source of the Nile; now, rugged researchers have delicately “sliced” through the jungle of the human genome to create a map of imprint control regions (ICRs) – creating the “imprintome” – to hasten our exploration of the epigenetic […]
Multimodal Nanopore Profiling of Circulating Tumor DNAAugust 1, 2022The Oxford Nanopore (ONT) sequencing platform may have more modalities than a Swiss army knife. In a multimodal masterpiece of a new study, researchers now demonstrate how DNA methylation, copy number alterations, nucleosome footprinting, and fragmentation profiles derived from liquid biopsies of cancer patients can deconvolute cellular composition and identify cancer-specific methylation changes from circulating […]
eBook: Epigenetics of CannabisJuly 21, 2022Changes in epigenetic regulation are hallmarks of the transition from normal to diseased cells. Exploration of the role of epigenetics in those who may use Cannabis, or related products such as THC or CBD, has proven to be informative for better understanding of their potential effects. In this EpiGenie ebook, we present summaries of several […]
Wake Up and Don’t Smell the Coffee! – How SARS-CoV-2-Induced DNA Methylation Impacts Your Sense of SmellJuly 18, 2022While many researchers have woken up, smelled the coffee, and realized the importance of epigenetic alterations in response to SARS-CoV-2 infections, many patients recovering from COVID-19 have been left unable to enjoy the olfactory joy of their first cup of java as each new day dawns. Now, well-caffeinated researchers led by Maria Lerm at Linköping […]
