The Power of Cooperation In Biosynthetic Coculture SystemsJuly 27, 2015Traditionally, most bioproduction culture systems use just one strain of yeast or bacteria. Sometimes, though, you just need a little help from your friends. That’s the idea behind the emerging field of synthetic ecology, which just achieved a major proof-of-principle success thanks to a team of MIT scientists. Cocultures have been used in specific cases […]
Human Nuclear Transfer and iPSCs: New Strategies for the Treatment of Mitochondrial DiseaseJuly 27, 2015We recently brought you news of an exciting study led by Juan Carlos Izpisua Belmonte in which his group successfully eliminated mutant mitochondrial (mt)DNA in oocytes to inhibit germline transmission of currently incurable mitochondrial diseases. Well he’s back, and this time he brought a friend. Â Shoukhrat Mitalipov has teamed up with Izpisua Belmonte in a […]
Stem Cell Derived Brain Orginoids Reveal a Root of AutismJuly 27, 2015Two cutting edge stem cell techniques have joined forces this week to produce a breakthrough in our understanding of the causes of Autism Spectrum Disorders (ASD). Years of study have gone into assessing if specific mutations in autism-associated genes contribute to the abnormal brain development observed in ASD with little or no luck. Seeing this […]
Webinar: Key Steps for Validating Antibodies and Optimizing the ChIP WorkflowJuly 27, 2015Abstract: Research in the field of epigenetics has grown at a rapid pace since the discovery of the first histone acetyltransferase enzymes 18 years ago. Since then, significant advances have been made in our understanding of the basic mechanisms of epigenetics (histone acetylation, histone methylation, chromatin remodeling and DNA methylation) and the impact of epigenetic […]
Salivating Insights into the DNA Methylation Connection in Fetal Alcohol SyndromeJuly 20, 2015Things often show up where you least expect. Whether it’s finding your keys in the freezer, your phone in the couch, English kings underneath a car park, or the secrets of brain development in spit. Sometimes all you have to do is look. Previously, the lab of Shiva Singh from the University of Western Ontario […]