Stem Cell Derived Brain Orginoids Reveal a Root of AutismJuly 27, 2015Two cutting edge stem cell techniques have joined forces this week to produce a breakthrough in our understanding of the causes of Autism Spectrum Disorders (ASD). Years of study have gone into assessing if specific mutations in autism-associated genes contribute to the abnormal brain development observed in ASD with little or no luck. Seeing this […]
Webinar: Key Steps for Validating Antibodies and Optimizing the ChIP WorkflowJuly 27, 2015Abstract: Research in the field of epigenetics has grown at a rapid pace since the discovery of the first histone acetyltransferase enzymes 18 years ago. Since then, significant advances have been made in our understanding of the basic mechanisms of epigenetics (histone acetylation, histone methylation, chromatin remodeling and DNA methylation) and the impact of epigenetic […]
Salivating Insights into the DNA Methylation Connection in Fetal Alcohol SyndromeJuly 20, 2015Things often show up where you least expect. Whether it’s finding your keys in the freezer, your phone in the couch, English kings underneath a car park, or the secrets of brain development in spit. Sometimes all you have to do is look. Previously, the lab of Shiva Singh from the University of Western Ontario […]
Race, Gender and Non-Coding RNA: tRNAs Don’t Play it Politically CorrectJuly 17, 2015Human genetics just got a whole lot more complicated with a report published last week by Isidore Rigoutsos’ team in Oncotarget. As if differences in expression profiles between cells, tissues and differentiation stages weren’t already enough, it seems that race and gender also affect genomic output. Specifically, the team focused on transfer RNAs (tRNAs). tRNAs […]
Resistance is Futile: Epigenetic Therapy Makes Cancer Cells DefenselessJuly 9, 2015A team of American scientists have shown that an epigenetic therapy might hold promise for combatting drug resistance in cancer. Cancer cells are masters of drug evasion and adept at using alternative pathways to give them an edge during treatment, complicating many therapeutic approaches. Overcoming drug resistance in cancer cells, would save millions of lives […]
