CHARMed I’m Shore: Meet the Latest Hotspots for DNA MethylationJanuary 19, 2009Between reading Dilbert cartoons and refilling their Swingline staplers, many of corporate America’s finest day dream of holidays to distant islands, but they’re not alone. Researchers studying DNA methylation have made minimal attempts to hide their infatuation with CpG islands, after all, these regions tend to associate themselves with prestigious protein-coding regions of genes. An […]
CAGEd miRNAs: Taming Transcriptional InitiationJanuary 18, 2009Most primary miRNA transcripts remain a mystery because they’re generally degraded by the time they leave the comfort of the nucleus. Where do the transcripts start? Do they have a single “peak” of initiation, or are there a variety of sites where they’re likely to begin? Limitations in the currently available molecular biology tool set […]
Summitting With PeakSeq.It’s About MappabilityJanuary 10, 2009ChIP-seq continues to assault bioinformatics teams with avalanches of data, but the upside of using this powerful approach brings some challenges along with it. Modeling background accurately requires a few tweaks, so before you get all excited about the double black diamond peaks that you’re seeing in regulatory motifs, you might want to factor in […]
EpiGenie FeaturesJanuary 10, 2009EpiGenie Features provide Insights into emerging trends, or sometimes just share technical tips from the experts in our community. View Features >>>
Latest Epigenetics HeadlinesJanuary 10, 2009Ever get that feeling that you forgot something? Well maybe you did, but it doesn’t have to be recent epigenetics research if you scope out our Headlines each week. That’s because we comb through all kinds of RSS feeds, email alerts, and reader feedback to bring you routine highlights from labs all around the world. […]
