T Cell Blockade Offers Safe Haven for Stem Cell TransplantsDecember 6, 2014As if human embryonic stem cells didn’t have enough trouble already making it through governmental legislation, they also face rejection from another source: the immune system. In their latest study, Herman Waldmann and his team of talented immunologists from the University of Oxford report a simple strategy to induce long-lasting immune tolerance to stem cell […]
Stem Cells Out of Position – A New Paradigm for Colorectal Cancer?December 5, 2014Colorectal cancer is, unfortunately, a common condition, making up 10% of global cancer cases. Therefore, a full understanding of the initiation and development of these tumor types should improve diagnosis and treatment decisions. A recent study from the University of Oxford has identified a potentially important mechanism of colorectal tumor formation that not only challenges current […]
Understanding How H3K4me1 Affects the Ageing Stem CellDecember 4, 2014Even though we don’t want to admit it, we all see changes in ourselves as the years pass by. A few more inches round the waistline here, and a little less muscle tone there, all due to a little less exercise and a little more food and drink! But what changes occur in our stem […]
Unwinding the Chromatin–Cancer ConnectionDecember 4, 2014There’s no denying that epigenetics and cancer are intimately intertwined, and that untangling this connection is vitally important in expanding our understanding of cancer initiation and development. Epigenetic signals are reversible regulators of gene expression and as such, make compelling targets in the study and treatment of cancer. As high-throughput data analysis becomes the norm, entire panels […]
EpiGenie Book Review: Epigenetics in PsychiatryDecember 3, 2014Epigenetics in Psychiatry brings together a collection of researchers in the field of neuroepigenetics to provide insight into research on the role of epigenetics in a range of psychiatric disorders, including schizophrenia, major depressive disorder, bipolar disorder and suicide. Not content with covering only these topics it also provides information on the techniques and animal models […]
