DNA Methylation: 2011 Editor’s FavoritesJanuary 11, 2012DNA methylation research had a little something for everyone in 2011. Not only was it linked to cancer, diet, post-traumatic stress, socio-economic status and heritability; but more was learned about 5-hydroxymethylcytosine as well. As if that wasn’t enough, two new cytosine variants, 5-formylcytosine and 5-carboxylcytsosine, joined the party this year too. We can’t wait to […]
Technology & Methods: 2011 Editor’s FavoritesJanuary 11, 2012Without advanced technology, epigenetic research would flounder. (You’d also probably be reading this on a stone tablet, which are really tricky to post on the web.) Check out our favorite improvements in technologies and methods from 2011 that are making sure epigenetic research is staying on the cutting edge. Single Cell Methylation Profiling The Restriction […]
Non-Coding RNA: 2011 Editor’s FavoritesJanuary 11, 2012Understanding of non-coding RNAs grew by leaps and bounds in 2011, but the more that we learn; the more we get the feeling that this is just the tip of the iceberg. Take a look at some of our favorite articles from the last year that highlights the variety of roles that non-coding RNA play. […]
Chromatin: 2011 Editor’s FavoritesJanuary 11, 2012Chromatin definitely left it’s mark in 2011, making big advances with applications in cancer, stem cell, environmental, and autism research, just to name a few. Check out our favorite chromatin articles from 2011 to help you get ready for what’s coming in 2012. Histone Harm from Nickel Exposure It’s been known for a while that […]
Valproic Acid Derivatives and Cisplatin: Better TogetherJanuary 10, 2012Like PB&J or Brangelina, some things are just better together. Now a new study suggests that combining derivatives of the histone deacetylase (HDAC) inhibitor valproic acid with the chemotherapy drug cisplatin may kill human lung cancer cells better than either drug alone. HDAC inhibitors such as valproic acid show great promise as treatments for a […]