Guide: Considerations for Choosing Effective ChIP AntibodiesAugust 24, 2012 With the expertise of Upstate® and Chemicon®, EMD Millipore has developed a comprehensive line of kits, assays, and antibodies for ChIP, so we understand the importance of choosing the right antibody for your ChIP experiment. In this guide, our research experts will share critical considerations for selecting an effective ChIP antibody. Download Print-Friendly […]
Splicing up Epigenetics with Dr. Shalini OberdoerfferAugust 23, 2012Dr. Shalini Oberdoerffer covers the role of splicing in epigenetics, how splicing and DNA methylation affect exon definition and the crosstalk between nucleosome and splicing mechanisms. Splicing Up Epigenetics In the splicing field several years ago, it was a somewhat surprising study coming out of whole genome sequencing studies of ChIP-seq data wherein it […]
Prediction Models Re-Write the Book on Nucleosome Occupancy and miRNA TargetingAugust 23, 2012A pair of newly released papers prove that you don’t always have to run more wet lab experiments to learn something new, you just need to look the data in a different way. The two research groups both used simulations and prediction algorithms, like the ones found on our Epigenetics Databases and Tools list, to […]
Bromodomain Inhibitor is the Male Contraception for the Ladies’ MouseAugust 22, 2012Mice from your backyard to Paris are buzzing with excitement after a team of scientists at Baylor may have paved the way for them to “mingle” with fewer consequences. The research team, led by Martin Matzuk, set out to explore ways to target, BRDT, a testes-specific, and bromo-domain containing protein that plays a key role […]
More than Methyltransferases: DNMTs Run a Reverse on 5hmCAugust 20, 2012New research out of Taiwan has found some familiar enzymatic faces are involved in the pathway from 5hmC to cytosine. A talented team of scientists recently showed that two members of the DNA methyltransferase (DNMT) family, DNMT3a and DNMT3b are more than just methyltransferases; they fill a role as dehydroxymethylases as well. It has already […]