CRISPR-Cas, Zinc Fingers and Epigenetic Editing with Dr. Marianne RotsFebruary 27, 2014Epigenetic Editing is an emerging field that has sparked interest across a number of research groups. By using a fusion of TET we can now target specific genomic regions for demethylation in order to learn about their function and regulation. We got in touch with one of the field’s experts, Dr. Marianne Rots, commissioning editor of Clinical Epigenetics, […]
Cells Take Epigenetic Cues from Tissue Environment, TooFebruary 19, 2014A ton of time and effort has been spent recently to detail how the external environment can shape our epigenome, but now Peter Jones and company at USC show that we shouldn’t underestimate the power of our internal environment. In a new published report, the USC team found that the extracellular cues taken from the surrounding tissue […]
DNA Methylation Detection In the Palm of Your HandFebruary 19, 2014Thanks to our never-ending obsession with miniaturizing technology and competitions like the Tricorder X-prize, it looks like everyone’s favorite piece of Star Trek medical paraphernalia, the Tricorder, may be just around the corner. A team from the University of Queensland has developed a new micro-device that creates a simple, rapid, and inexpensive strategy for detecting DNA […]
Go Into the Light With Promega HDAC-Glo™ 2/IIa AssaysFebruary 18, 2014Searching for that next great HDAC inhibitor can be a grueling task, but now the R&D team at Promega has just introduced the HDAC-Glo™ 2 and IIa Assays to make your HDAC screening life a whole lot better. Just like the rest of the HDAC-Glo™ Assay family, the HDAC-Glo™ Class IIa and HDAC-Glo™ 2 Assays […]
NOMe-Seq Secrets RevealedFebruary 17, 2014You’ve read the NOMe-seq (Nucleosome Occupancy and Methylome sequencing) papers. Seen the splashy advertisements. Now, we’ve consulted with the experts at Active Motif to get the inside scoop on how to get started, and get the most out of your NOMe-seq experience. NOMe-Seq was originally published and developed by researchers in the Peter Jones lab […]
