Architectural Woes Prompt Age-related Problems Thanks to Genes Lacking CpG IslandsJanuary 20, 2022As cracks to walls and beams can lead to an old house coming apart at the seams, the architectural alterations associated within an aging nucleus can prompt degenerative processes at the cell and tissue level. While any good architect can identify and help to sure up the problematic elements bringing down the house, the blueprints […]
scAge – A Single-cell DNA Methylation Clock Details Epigenetic Aging and RejuvenationJanuary 10, 2022With the new year comes a fresh start, but does the aging epigenome of each one of our cells share this sentiment? To help get your new year off to the right start, a new program known as “scAge” allows the determination of the age of single cells via DNA methylation and reveals insight into […]
A Suite of New Tools to Solve Single-cell Epigenetic EnigmasDecember 23, 2021Welcome explorers of the epigenome! Are you looking for new tools to help answer the toughest of epigenetic enigmas? Then check out this suite of single-cell methods papers from technologically-talented teams led by Aviv Regev (Broad Institute of MIT and Harvard) and collaborators. inCITE into How Transcription Factors Shape In Vivo Gene Expression A collaboration […]
A Youthful Brain Boost via DNA Hydroxymethylation: TET1 Enters the Myelin Repair Technician’s ToolkitDecember 13, 2021Does it feel like your aging brain cells have been firing a little slower lately? Why not refresh your connection and speed up your synaptic signal transmission with a visit from your oligodendrocyte myelin repair technicians. Their youthful TET1 and DNA hydroxymethylation repair kit will bring you back to fiber-optic speeds in no time. This […]
A Circulating microRNA Makes a Macro Difference in the Battle Against COVID-19November 28, 2021From holding the door open to passing on a link to an exciting epigenetics paper – small gestures can make an enormous difference to anyone’s day! Now, an exciting new study suggests that the expression of a microRNA has a macro impact during SARS-CoV-2 infection and could represent an important target for the treatment of […]
