How Active are Your HDACs? Abcam HDAC & SIRT Activity Assay KitsJuly 25, 2013Based on their booming popularity lately, it seems that histone deacetylases (HDACs) and sirtuins (SIRTs) lead pretty active epigenetic lives. As the experiments continue, there are several reasons why the epigenetics research community would want to keep tabs on what HDACs and SIRTs are doing including: Assessing HDAC or SIRT purification Screening for HDAC/SIRT inhibitors […]
Epigenetics: Damage Control in the Cell with Dr. Jim HaberJuly 25, 2013Dr. Haber discusses how normal cells deal with DNA damage and genomic integrity; and how those systems go awry in cancer cells. Epigenetics: Damage Control in the Cell Well, I work in an area of DNA repair. And what we have come to realize over the last decade is how these repair mechanisms prevent cells […]
Vitamin C in Media Critical for ES Cell 5hmCJuly 24, 2013Whether its pop culture (like the ongoing royal baby mania) or cell culture, there’s no denying the enormous impact that ‘media’ has on our life. In fact, new evidence shows that a little Vitamin C in cell culture media can influence mouse embryonic stem (ES) cells, like typical pre-teens, to undergo a blastocyst-like identity crisis. […]
The Dynamic EpigenomeJuly 24, 2013EpiGenie recently reviewed the text Epigenetics by Jorg Tost. Here is a more in depth summary of one the chapters provided courtesy of JA Gill who is molecular biologist at NOAA in the Northwest Fisheries Science Center, to give you a little sneak peek into what the whole book is all about: The Dynamic Epigenome: […]
Placental miRNAs Predict Infant BehaviorJuly 18, 2013Many parents consider their children’s behavior to be a bit of a mystery, (just ask anyone who has shared a plane ride with an unruly toddler) but new miRNA research hints that it may soon be possible to predict your child’s behavioral traits by a simple non-invasive test right after birth. A fortune telling team […]
