Psychosis Moderates the Association Between Cannabis Use and DNA MethylationOctober 28, 2024Analyzing the DNA methylation alterations induced by cannabis use has provided a wealth of evidence of potential harms, with recent studies focusing on neurodevelopmental problems after prenatal exposure, increased risk of adverse health outcomes, and accelerated epigenetic aging. Now, a study reports the first epigenome-wide association study (EWAS) exploring the interplay between cannabis use, DNA […]
eBook: CRISPR & Gene Editing 2024October 17, 2024CRISPR/Cas-mediated gene editing represents a straightforward and accurate process; however, the widespread therapeutic application of this technology still requires the precise characterization of both on- and off-target activity. In this eBook, we highlight a recent group of publications and methods using this powerful technique! Contents: Epigenetic Machinery Fights Back! SARS-CoV-2 RNA Modifications Inhibit Replication and […]
Children Prenatally Exposed to Cannabis Have Altered DNA MethylationOctober 7, 2024As more states legalize and decriminalize cannabis, more questions are being raised about its effects, especially on pregnancy. Now, a clear-thinking team sees through the haze and shows that maternal cannabis use during pregnancy is associated with epigenome-wide differential DNA methylation in the blood of exposed children, especially in genes involved in neurodevelopment. Studies have shown […]
Epigenetic Two-factor Authentication Secures Male Fertility from the Insider Threat of TransposonsOctober 7, 2024Two-factor authentication represents a modern approach to securing our digital lives from outside threats; however, research now suggests that this concept may not be so modern. A new study now reveals that male germ cells employ a piRNA-mediated epigenetic “two-factor authentication” strategy to secure the precisely timed DNA methylation-induced silencing of insider threats that impact […]
Metformin Keeps Aging Primate Epigenomes “In Form”September 30, 2024Those of us feeling the all too familiar effects of time may look to cut back on certain “excesses” and keep fit (in both body and mind) to maintain a healthy aging process. Now, a team of fitness enthusiasts has revealed that long-term treatment with the diabetes drug metformin maintains an aging population of monkeys […]
