Predicting Gene Expression with Chromatin FeaturesSeptember 11, 2012As any weather forecaster can tell you, making accurate predictions is tough. But researchers now report that they’ve confirmed the power of chromatin features to predict gene expression. They’ve also come up with some new insights, too. Sure, some histone mods are associated with transcriptional repression, whereas others typically mark active spots. But many studies […]
Promoters Reach Out to Far -Away ElementsSeptember 11, 2012Now that the Olympic games are over, researchers in the ENCODE consortium have announced that they’ve just finished another Olympic effort of their own—the large-scale mapping of functional elements in the human genome. And just like the flexible “Fierce Five” U.S. women’s gymnastics team, it turns out that the genome is very bendy, looping around […]
Guide: Considerations for Choosing Effective ChIP AntibodiesAugust 24, 2012 With the expertise of Upstate® and Chemicon®, EMD Millipore has developed a comprehensive line of kits, assays, and antibodies for ChIP, so we understand the importance of choosing the right antibody for your ChIP experiment. In this guide, our research experts will share critical considerations for selecting an effective ChIP antibody. Download Print-Friendly […]
Splicing up Epigenetics with Dr. Shalini OberdoerfferAugust 23, 2012Dr. Shalini Oberdoerffer covers the role of splicing in epigenetics, how splicing and DNA methylation affect exon definition and the crosstalk between nucleosome and splicing mechanisms. Splicing Up Epigenetics In the splicing field several years ago, it was a somewhat surprising study coming out of whole genome sequencing studies of ChIP-seq data wherein it […]
Prediction Models Re-Write the Book on Nucleosome Occupancy and miRNA TargetingAugust 23, 2012A pair of newly released papers prove that you don’t always have to run more wet lab experiments to learn something new, you just need to look the data in a different way. The two research groups both used simulations and prediction algorithms, like the ones found on our Epigenetics Databases and Tools list, to […]
