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Stem Cell News

Reprogramming Roadmap Reveals Fuzzy New Stem Cells

Induced pluripotent stem cell (iPSCs) research burst on to the scene in 2006 with a paper which has since spawned thousands of studies and has proved to be a quantum leap for regenerative medicine. … [Read More...]

chromatin

Enter the Histone: H2A.Z Controls Memory

Memory is one fancy cellular function that seems to be the niche of the epigenome. Through it a cell can remember its identity and past exposures. But what about that other type of memory? Ya know, … [Read More...]

Stem Cell News

Promoting Pluripotency: Vitamin C Modulates Stem Cell Specifc miRNAs

We all know “an apple a day, keeps the doctor away”, but it requires a lot of discipline to ensure that our diet contains enough vitamins. This holds especially true for the daily vitamin C uptake. … [Read More...]

Stem Cell News

Alpha-ketoglutarate modifies DNA methylation and promotes stem cell pluripotency

Many of us go through the morning ritual of picking up store-brewed coffee, although we could just as easily make it ourselves. Most mammalian cells feel the same about glutamine, which they require … [Read More...]

non-coding-rna

Dynamic Pseudouridylation of ncRNA and mRNA

Pseudouridine (Ψ) is not only the most abundant post-translational modification (PTM) of RNA in all organisms, but it is also amongst the first discovered, way back in the futuristic 50's, where it … [Read More...]

chromatin

Epigenetic Exploitation of Host Cells by Viruses

Exploitation is a common theme in all fields of biology and viruses are no exception. But now it seems that viruses are up to some creative tricks when it comes to keeping a low profile in preparation … [Read More...]

Stem Cell News

Epigenetics Mediates Immortality of Adult Stem Cells

What would you do to ensure your immortality? Drink a potion? Cast a spell? Or even set out on an expedition to find the fountain of youth? Researchers from the Adult Stem Cell Technology Centre in … [Read More...]

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Stem Cell News

Reprogramming Roadmap Reveals Fuzzy New Stem Cells

Induced pluripotent stem cell (iPSCs) research burst on to the scene in 2006 with a paper which has since spawned thousands of studies and has proved to be a quantum leap for regenerative medicine. … [Read More...]

non-coding-rna

Dynamic Pseudouridylation of ncRNA and mRNA

Pseudouridine (Ψ) is not only the most abundant post-translational modification (PTM) of RNA in all organisms, but it is also amongst the first discovered, way back in the futuristic 50's, where it … [Read More...]

chromatin

Epigenetic Exploitation of Host Cells by Viruses

Exploitation is a common theme in all fields of biology and viruses are no exception. But now it seems that viruses are up to some creative tricks when it comes to keeping a low profile in preparation … [Read More...]

Stem Cell News

Nuclear Transfer vs Induced Pluripotency for Creating Human Stem Cells

Have you ever wish you could just clone yourself? How much more work you’d be able to get done in a day! While creating an exact copy of yourself that knows everything you do is still very much in the … [Read More...]

Stem Cell News

New Dimensions for Pluripotent Cell Differentiation

The recent Hollywood trend of adapting much beloved movies from two-dimensional (2D) into 3-dimensional (3D) offerings hasn’t met with the expected fanfare and applause. However, strategies which have … [Read More...]

Stem Cell News

On the Trail of Naïve Human Pluripotent Cells

The creation of pluripotent stem-cell lines from early embryos has enabled the indefinite capture in vitro of one of nature’s most fascinating but fleeting faces. Yet, not all embryonic stem cells … [Read More...]

chromatin

Calling ChIP-seq Differential Peaks Gets Easier: Two New Tools

Sometimes bioinformatics can seem a bit mystical, particularly when a tool arrives that makes you wonder what you were wasting your time doing before it. ChIP-seq is no stranger to this world and as a … [Read More...]

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Stem Cell News

Boosting Bone by Exercising your Stem Cells

How do you do it? Running? Boxing? Jane Fonda work out videos? Whatever the method, we all need exercise to keep our bodies and minds healthy and functional, and it now turns out that stem cells … [Read More...]

SYNb

Combating Compensation: Generation of a Human Haploid Cell Line

Cas9 has already been shown to be able to knock out up to kilobase-size fragments of DNA, making it a big hitter in the world of genome editing. But one of the biggest enemies for researchers using … [Read More...]

chromatin

Calling ChIP-seq Differential Peaks Gets Easier: Two New Tools

Sometimes bioinformatics can seem a bit mystical, particularly when a tool arrives that makes you wonder what you were wasting your time doing before it. ChIP-seq is no stranger to this world and as a … [Read More...]

SYNb

Lipid-Mediated Delivery of Genome Editing Proteins

In today's culture negativity is usually frowned upon; maintaining a positive outlook is almost essential to a successful scientific career, but an innovative team of researchers have put some … [Read More...]

dna-methylation

Multiplexed Targeting of DNMTs Made Possible by CRISPR

Adding to the ever growing potential of genome editing, one of the latest breakthroughs from the lab of Feng Zhang at the Broad Institute of MIT and Harvard puts CRISPR/Cas9 to the test with an … [Read More...]

chromatin

Histone Modification Reading Domains Crack Complex Combos

Having alternatives is always great, particularly when it comes to studying histone modifications.  By using some recombinant proteins of histone reading domains, researchers from the lab of Albert … [Read More...]

Stem Cell News

Pluripotency Genes are Loopy about their Neighborhood

Most of us understand the importance of a good neighborhood; we look for somewhere to reflect our identity and to bring us together with similar minded people. Interestingly, recent work from the labs … [Read More...]

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microRNAs Europe Meeting 2014

The microRNAs Europe Meeting is perhaps one of the best-kept secrets in the non coding RNA community. Similar to thos...

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Epigenomics of Common Diseases 2014

The 4th Wellcome Trust Epigenomics of Common Diseases conference in Cambridge brought together leading sci...

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Epigenetic plasticity: Implications in Neural (dys)function 2014

The latest EMBO workshop was held in ICVS in Braga on October 22-25th and focused on the state-of-the-art ...

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Chromatin and Epigenetics: From Omics to Single Cells

Abcam and co-organizers once again pulled off a delightful meeting – this time bridging two exciting approaches...

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World Congress of Psychiatric Genetics 2014

Copenhagen provided the scenic backdrop for this year’s World Congress of Psychiatric Genetics. About 883 participa...

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Nuclear RNA, Gene Regulation, and Chromatin Structure (2014 IMB Conference)

The 2014 IMB Meeting on Nuclear RNA, Gene Regulation, and Chromatin Structure took place from the 9t...

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Transcription and Chromatin

“An All-star lineup of presenters and a pleasant atmosphere made the 11th EMBL Transcription and Chromat...

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