Latest Updates

Stay on top of epigenetics, stem cell, and synthetic biology research with the latest headlines, special features, technology highlights, and conference action.

SYNb

CRISPR/Cas9 Gets Genes all Turned On With a Bit of Blue Light

Guess what? It seems that blue light has a lot more to offer than just helping with your winter time blues. It could also be just what your transcriptional activation system needs. Synthetic biology … [Read More...]

non-coding-rna

microRNAs Get a Second Job: Role in m6A RNA Methylation and Reprogramming

It’s no secret that microRNAs are pretty busy molecules. A single microRNA can regulate the expression of several, maybe even hundreds, of transcripts. If that wasn’t enough, researchers at … [Read More...]

chromatin

Getting started with Chromatin Conformation Capture (3C)

The concept of chromatin contact mapping, or determining the three-dimensional structure conformation and interactions of chromatin domains, is now a reality because of Chromatin Conformation Capture … [Read More...]

SYNb

Taming Transcription in Synthetic Gene Circuits

As a kid there was no greater feeling on a weekend shopping trip than being set loose on the Pick ‘N’ Mix, carefully choosing from the wealth of candy to create the perfect selection. Lucky for you … [Read More...]

chromatin

ChIP 2.0: Guide to Advanced Chromatin Immunoprecipitation Techniques

Chromatin immunoprecipitation (ChIP) is the basis for much of modern chromatin analysis technologies. The central principle of ChIP is the use of an antibody targeting a protein or histone … [Read More...]

SYNb

Plant Receptor Re-engineered to Hear “Drought!” From a New Signal

Don’t get me wrong, plants have a lot of things going for them. However, as Groot’s fellow Galaxy Guardians can attest, vocabulary isn’t one of them. It can be hard to communicate with plants, even … [Read More...]

non-coding-rna

Researchers Use Their PreSTIGE to Connect lncRNAs and Tissue-specific Gene Expression

Predicting tissue-specific enhancers is a tricky business. While histone marks such as H3K4me1 and binding of p300 are good enhancer predictors, pointing out which enhancers are tissue-specific is … [Read More...]

View All Latest
SYNb

CRISPR/Cas9 Gets Genes all Turned On With a Bit of Blue Light

Guess what? It seems that blue light has a lot more to offer than just helping with your winter time blues. It could also be just what your transcriptional activation system needs. Synthetic biology … [Read More...]

non-coding-rna

microRNAs Get a Second Job: Role in m6A RNA Methylation and Reprogramming

It’s no secret that microRNAs are pretty busy molecules. A single microRNA can regulate the expression of several, maybe even hundreds, of transcripts. If that wasn’t enough, researchers at … [Read More...]

chromatin

Getting started with Chromatin Conformation Capture (3C)

The concept of chromatin contact mapping, or determining the three-dimensional structure conformation and interactions of chromatin domains, is now a reality because of Chromatin Conformation Capture … [Read More...]

chromatin

ChIP 2.0: Guide to Advanced Chromatin Immunoprecipitation Techniques

Chromatin immunoprecipitation (ChIP) is the basis for much of modern chromatin analysis technologies. The central principle of ChIP is the use of an antibody targeting a protein or histone … [Read More...]

non-coding-rna

Researchers Use Their PreSTIGE to Connect lncRNAs and Tissue-specific Gene Expression

Predicting tissue-specific enhancers is a tricky business. While histone marks such as H3K4me1 and binding of p300 are good enhancer predictors, pointing out which enhancers are tissue-specific is … [Read More...]

dna-methylation

The Path to Cell Transformation is Paved with Methylome Modifications

Whether it’s making the monumental move to high school, switching jobs or experiencing the culture shock from moving countries, adjusting to a new environment isn’t always easy. Often we have to make … [Read More...]

chromatin

Review: Crosslinking-Immunoprecipitation (CLIP) Methods

RNA-protein interactions are key to understanding human health and disease. Crosslinking-immunoprecipitation (CLIP) and related technologies are powerful tools for characterizing these interactions. … [Read More...]

View All Epigenetics
SYNb

CRISPR/Cas9 Gets Genes all Turned On With a Bit of Blue Light

Guess what? It seems that blue light has a lot more to offer than just helping with your winter time blues. It could also be just what your transcriptional activation system needs. Synthetic biology … [Read More...]

SYNb

Taming Transcription in Synthetic Gene Circuits

As a kid there was no greater feeling on a weekend shopping trip than being set loose on the Pick ‘N’ Mix, carefully choosing from the wealth of candy to create the perfect selection. Lucky for you … [Read More...]

SYNb

Plant Receptor Re-engineered to Hear “Drought!” From a New Signal

Don’t get me wrong, plants have a lot of things going for them. However, as Groot’s fellow Galaxy Guardians can attest, vocabulary isn’t one of them. It can be hard to communicate with plants, even … [Read More...]

SYNb

Transcriptional Activation: a New Trick for CRISPR-Cas9

We all know that the genome editing superhero CRISPR-Cas9 is a master of modifying the genome, but a recent paper from Zhang lab shows that it is more than just a one-trick pony. This latest research … [Read More...]

SYNb

Cell Organelles Trip the Light Fantastic with Optogenetics

The future is looking bright for optogenetics – a technique which uses light to control cellular processes. Following on from a previous illuminating study covered here at Epigenie (Shedding Light on … [Read More...]

SYNb

SynBioLGDB: A Gateway for Logical Biology

Electrical engineering is a strong contender for the central analogy of synthetic biology. Synthetic biologists often think of electrical circuits when designing gene networks, and logic gates are … [Read More...]

SYNb

Auditing the Editors: Monitoring Off-Target Activity of Genome Editing

While the fashion and music tastes of the late 1980’s was rather questionable, it was a time of historic technological and societal change. Between the breakdown of the Soviet Union and the rise of … [Read More...]

View All Synthetic Biology
non-coding-rna

microRNAs Get a Second Job: Role in m6A RNA Methylation and Reprogramming

It’s no secret that microRNAs are pretty busy molecules. A single microRNA can regulate the expression of several, maybe even hundreds, of transcripts. If that wasn’t enough, researchers at … [Read More...]

Stem Cell News

Radiated Rodents Get Remyelinated Thanks to Stem Cell Treatment

Radiotherapy is an important and effective tool in the war against cancer, but its use for treating brain tumors brings with it unwanted side effects that can cause long term suffering to the patient. … [Read More...]

Stem Cell News

A Brief History of Cellular Transdifferentiation

For centuries, some of the world’s leading scholars worked endlessly with one objective, to turn ordinary metals into gold. Now, scientists of the 21st century are trying their hand at another type of … [Read More...]

Stem Cell News

Heritable Epigenetic Predisposition to Reprogramming

If epigenetics has taught us anything, it is that not all genetically identical beings are created equal. A team of stem-cell researchers from Tel Aviv University led by Iftach Nachman now apply this … [Read More...]

Stem Cell News

A Reprogramming Revolution? Cost-Effective Method of Creating Pluripotent Stem Cells

“We can rebuild him. We have the technology. We can make him better than he was. Better, stronger, faster”. They did it for Steve Austin in The Six Million Dollar Man, and now researchers from the … [Read More...]

Stem Cell News

Hair-Raising Research: Embryonic Stem Cells Could Help Battle Baldness

Throw away those tonics! Bin those balms! Hide those hairpieces! We bring great news for those who are losing more than the average of 100 hairs per day. In a set of hair-raising experiments … [Read More...]

Stem Cell News

A SIRT-an Link Between Metabolism, Stem Cell Function and Epigenetics

In our younger years our rampant metabolism meant we could eat what we wanted with little or no consequences. However, as we get older, our metabolism somehow gets “reprogrammed”, meaning all that … [Read More...]

View All Stem Cells

microRNAs Europe Meeting 2014

The microRNAs Europe Meeting is perhaps one of the best-kept secrets in the non coding RNA community. Similar to thos...

[Read More]

Epigenomics of Common Diseases 2014

The 4th Wellcome Trust Epigenomics of Common Diseases conference in Cambridge brought together leading sci...

[Read More]

Epigenetic plasticity: Implications in Neural (dys)function 2014

The latest EMBO workshop was held in ICVS in Braga on October 22-25th and focused on the state-of-the-art ...

[Read More]

Chromatin and Epigenetics: From Omics to Single Cells

Abcam and co-organizers once again pulled off a delightful meeting – this time bridging two exciting approaches...

[Read More]

World Congress of Psychiatric Genetics 2014

Copenhagen provided the scenic backdrop for this year’s World Congress of Psychiatric Genetics. About 883 participa...

[Read More]

Nuclear RNA, Gene Regulation, and Chromatin Structure (2014 IMB Conference)

The 2014 IMB Meeting on Nuclear RNA, Gene Regulation, and Chromatin Structure took place from the 9t...

[Read More]

Transcription and Chromatin

“An All-star lineup of presenters and a pleasant atmosphere made the 11th EMBL Transcription and Chromat...

[Read More]
View All