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Stay on top of epigenetic's and non-coding RNA research with the latest headlines, special features, technology highlights, and conference action.

dna-methylation

Universal DNA Methylation Signature of Solid Tumors

It seems that cancer is joining the minimalist trend, and has recently been caught sporting a universal and distinct DNA methylation signature. A talented team from John Hopkins lead by … [Read More...]

chromatin

3D Epigenome Folding Models

Much like 3D pictures enhance the illusion of depth of picture perception, polymer physics can enhance the depth of organization of epigenomic landscape in topologically associated 3D loop … [Read More...]

dna-methylation

Alzheimer Disease Gets Brain Region Specific EWAS

Epigenome-wide association studies (EWAS) appear to be the natural evolution of GWAS that has given neuroscience a epigenomic renaissance. Jonathan Mill and team from the University of Exeter Medical … [Read More...]

technology

University of Ulster Stem Cell Biology Postgrad Diploma

The University of Ulster is offering an entirely online, postgraduate diploma course in Stem Cell Biology and it's starting soon. The course is designed to allow students to break into, or advance in … [Read More...]

non-coding-rna

Argonaute CLIP-Seq Reveals miRNA Targetome Diversity Across Tissue Types

First epigenetics knocked Mendel off the high horse of simple inheritance and now it's taking a shot at Watson and Crick. It seems that not even base-pairing is safe these days, with microRNA … [Read More...]

technology

CRISPR/Cas9 Get Upgraded sgRNA Targeting

The Crispr/Cas9 genome editing system has risen to fame so quickly it appears to be suffering from a case of the bends. Researchers at Johns Hopkins University however have just given it a bit more … [Read More...]

technology

Patient Specific iPSCs Team Up with CRISPR/Cas9

Some villains are so tough that it might take a few heroes to take them on. β-thalassemia is just that evil, an all too common genetic disease at the worldwide level. Caused by simple mutations in … [Read More...]

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technology

Genome Editing Timeline

Since its inception, the field of genetic engineering has introduced DNA to plenty of nips, tucks, and modifications all in the name of science. The latest evolution of these, genome editing, might be … [Read More...]

dna-methylation

The Embryonic Journey of DNA Methylation Dynamics

Two recent Nature papers made big strides in understanding mammalian embryonic DNA methylation. The Meissner and Eggan team from Harvard focused in on CpG dynamics and how they compare to mice, … [Read More...]

technology

Webinar: Using CRISPR/Cas9 Technology for Editing Genes in Haematopoietic Cells and Mice

Presented by: Dr Marco Herold, Laboratory Head, Molecular Genetics of Cancer Division, The Walter & Eliza Hall Institute of Medical Research Abstract: The CRISPR/Cas9 technology provides an … [Read More...]

chromatin

Webinar – Bringing ChIP Seq Data into Focus: Advanced Normalization Strategies

If you've ever struggled to make sense of your ChIP Seq data, then check out this webinar presented by our colleagues at Active Motif, to get some ideas on how to bring some order to the chaos of … [Read More...]

non-coding-rna

Sometimes miRNAs Go the Other Way

The nightly news lately makes it seem like the world has gone upside down, and now we've got some science to back it. Honglei Zhou and Isidore Rigoutsos from Thomas Jefferson University recently … [Read More...]

dna-methylation

Going Global with DNA Methylation Analysis

It's human nature to get enthralled by the latest, shiny new technology on the market, but sometimes a more established approach is just as effective. We recently connected with our friends at Zymo … [Read More...]

dna-methylation

Kit Competition Reveals Hacks to Help Bisulfite Conversion

At first pass it may seem like all bisulfite conversion kits are essentially the same – and for the most part, that’s true. But according to a recently published evaluation, the conversion is all in … [Read More...]

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technology

CRISPR/Cas9 Get Upgraded sgRNA Targeting

The Crispr/Cas9 genome editing system has risen to fame so quickly it appears to be suffering from a case of the bends. Researchers at Johns Hopkins University however have just given it a bit more … [Read More...]

technology

Patient Specific iPSCs Team Up with CRISPR/Cas9

Some villains are so tough that it might take a few heroes to take them on. β-thalassemia is just that evil, an all too common genetic disease at the worldwide level. Caused by simple mutations in … [Read More...]

technology

Gazing at Your Local Epiproteome with CRISPR-ChAP-MS

For those of you who were thinking the CRISPR/Cas9 system was just limited to genome editing, think again because the story just got a new twist. Almost like combining the bullet speed of Superman … [Read More...]

technology

Editor in Chief: TALEN, CRISPR and the iPSC Genome

Undeniably, the future of therapeutics is moving away from panacea miracle drugs and gravitating towards personalized treatments using gene therapy. Furthermore, the discovery of iPSCs verified the … [Read More...]

technology

Webinar: Using CRISPR/Cas9 Technology for Editing Genes in Haematopoietic Cells and Mice

Presented by: Dr Marco Herold, Laboratory Head, Molecular Genetics of Cancer Division, The Walter & Eliza Hall Institute of Medical Research Abstract: The CRISPR/Cas9 technology provides an … [Read More...]

technology

TAL Effectors Dig the Long Distance Thing

If you think the subway is crowded you haven’t seen what a TAL Effector (TALE) has to put up with when getting to work. In a new study involving the production of more than 200 TALE modulators, … [Read More...]

technology

CRISPRs and TALENs Stay on Target in Stem Cell Genomes

Some of our most touted advancements in weaponry involve ‘surgical strike capabilities’, the idea being that the more precisely you attack a specific target, the less unintended damage there will be.  … [Read More...]

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EpiCongress-Boston 2014

Hanson Wade’s EpiCongress events have become a mainstay in the field, and offer a unique blend of academic and ...

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Canadian Conference on Epigenetics: Epigenetics, Eh! 2014

EpiGenie uses more Canadian talent than the NHL, so naturally we sent one of our staff ...

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RNA-Seq 2014

This year’s RNA-Seq Summit looked to be as interesting as ever, with some great work b...

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Cambridge Epigenetics Symposium 2014

Not knowing exactly what to expect from this brand new symposium, we were excited to see what the Cambridge Epigeneti...

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Linking Metabolism to Epigenetics 2014

Abcam continued it’s trend of putting together unique and cutting edge events with the Crossing Boundaries: Lin...

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Chromatin: from Nucleosomes to Chromosomes

The Welcome Trust Chromatin meeting always draws a ton of interest from the EpiGenie crew, so we were anxious to see ...

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Long Noncoding RNAs: Marching toward Mechanism

Keystone always puts on some of the premier non-coding RNA meetings every year, and this was no exception. Our friend...

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