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Stay on top of epigenetic's and non-coding RNA research with the latest headlines, special features, technology highlights, and conference action.

dna-methylation

Environmental enrichment stimulates neural 5hmC dynamics

Judging from the luxurious lifestyles of the rich and famous, it would seem there's no denying the wonders of an enriched environment. Even at an epigenetic scale, enhancing your environment properly … [Read More...]

non-coding-rna

Mighty Morphin’ miRNA isomiRs

While microRNAs have been generally thought of as very homogenous little genomic modulators, some new studies are finding that there is actually an entire miRNA cosmos out there with slight variations … [Read More...]

dna-methylation

Rewiring Stem Cell Transcriptional Circuitry

It seems all that was needed for human stem cells to maintain their pluripotent state, was just a little transcriptional rewiring. This cellular circuitry wasn't handled by a master electrician … [Read More...]

chromatin

Webinar: “Precision Mapping”- High Resolution Mapping using ChIP-exo

Don't forget to check out our upcoming webinar featuring the inner workings of the powerful ChIP exo technique. Sign up now, to make sure you don't miss out. "Precision Mapping" - High Resolution … [Read More...]

dna-methylation

How to Design Bisulfite Primers

The bisulfite conversion experts from Zymo Research have put together a killer guide on the ins and outs of amplifying bisulfite treated DNA.  EpiGenie got an exclusive, advanced peek at some of the … [Read More...]

technology

Endogenous Retroviruses Shape the Road to Stem Cell Reprogramming

It’s been a while now since Yamanaka and his team discovered the recipe of everlasting youth, for cells at least. Yet, the road leading from differentiated cell to pluripotency passes through largely … [Read More...]

dna-methylation

Reduced Representation 5hmC and 5mC Array

Differentiating between DNA's celebrity cytosine bases can be harder than remembering all the 'celebrities' caught in hollywood's latest photo leak. But have no fear, because oxidative bisulfite … [Read More...]

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chromatin

Webinar: “Precision Mapping”- High Resolution Mapping using ChIP-exo

Don't forget to check out our upcoming webinar featuring the inner workings of the powerful ChIP exo technique. Sign up now, to make sure you don't miss out. "Precision Mapping" - High Resolution … [Read More...]

dna-methylation

How to Design Bisulfite Primers

The bisulfite conversion experts from Zymo Research have put together a killer guide on the ins and outs of amplifying bisulfite treated DNA.  EpiGenie got an exclusive, advanced peek at some of the … [Read More...]

chromatin

Get In Tune with Chromatin: Abcam High Sensitivity ChIP Kits

Today’s epigenetics researchers need to squeeze every last bit of detail from the chromatin immunoprecipitation (ChIP) experiments they run. That’s why Abcam launched their new High Sensitivity ChIP … [Read More...]

dna-methylation

EpiGenie Book Reviews: Epigenetics in Psychiatry

Weighing in at just above 600 pages, Epigenetics in Psychiatry sets out to cover emerging research interests in the world of neuroepigenomics and it's translation to the clinic. A collection of … [Read More...]

technology

Genome Editing Timeline

Since its inception, the field of genetic engineering has introduced DNA to plenty of nips, tucks, and modifications all in the name of science. The latest evolution of these, genome editing, might be … [Read More...]

dna-methylation

The Embryonic Journey of DNA Methylation Dynamics

Two recent Nature papers made big strides in understanding mammalian embryonic DNA methylation. The Meissner and Eggan team from Harvard focused in on CpG dynamics and how they compare to mice, … [Read More...]

technology

Webinar: Using CRISPR/Cas9 Technology for Editing Genes in Haematopoietic Cells and Mice

Presented by: Dr Marco Herold, Laboratory Head, Molecular Genetics of Cancer Division, The Walter & Eliza Hall Institute of Medical Research Abstract: The CRISPR/Cas9 technology provides an … [Read More...]

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chromatin

Webinar: “Precision Mapping”- High Resolution Mapping using ChIP-exo

Don't forget to check out our upcoming webinar featuring the inner workings of the powerful ChIP exo technique. Sign up now, to make sure you don't miss out. "Precision Mapping" - High Resolution … [Read More...]

dna-methylation

Reduced Representation 5hmC and 5mC Array

Differentiating between DNA's celebrity cytosine bases can be harder than remembering all the 'celebrities' caught in hollywood's latest photo leak. But have no fear, because oxidative bisulfite … [Read More...]

technology

CRISPR/Cas9 Get Upgraded sgRNA Targeting

The Crispr/Cas9 genome editing system has risen to fame so quickly it appears to be suffering from a case of the bends. Researchers at Johns Hopkins University however have just given it a bit more … [Read More...]

technology

Patient Specific iPSCs Team Up with CRISPR/Cas9

Some villains are so tough that it might take a few heroes to take them on. β-thalassemia is just that evil, an all too common genetic disease at the worldwide level. Caused by simple mutations in … [Read More...]

technology

Gazing at Your Local Epiproteome with CRISPR-ChAP-MS

For those of you who were thinking the CRISPR/Cas9 system was just limited to genome editing, think again because the story just got a new twist. Almost like combining the bullet speed of Superman … [Read More...]

Rapid Assessment of CRISPR Genome Editing

Well begun is half done. But if you are making a CRISPR knock-out mouse, it is hard to tell early enough whether you’ve begun well. Thankfully, a talented team of researchers in Japan led by Takayuki … [Read More...]

technology

Editor in Chief: TALEN, CRISPR and the iPSC Genome

Undeniably, the future of therapeutics is moving away from panacea miracle drugs and gravitating towards personalized treatments using gene therapy. Furthermore, the discovery of iPSCs verified the … [Read More...]

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Transcription and Chromatin

“An All-star lineup of presenters and a pleasant atmosphere made the 11th EMBL Transcription and Chromat...

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EpiCongress-Boston 2014

Hanson Wade’s EpiCongress events have become a mainstay in the field, and offer a unique blend of academic and ...

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Canadian Conference on Epigenetics: Epigenetics, Eh! 2014

EpiGenie uses more Canadian talent than the NHL, so naturally we sent one of our staff ...

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RNA-Seq 2014

This year’s RNA-Seq Summit looked to be as interesting as ever, with some great work b...

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Cambridge Epigenetics Symposium 2014

Not knowing exactly what to expect from this brand new symposium, we were excited to see what the Cambridge Epigeneti...

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Linking Metabolism to Epigenetics 2014

Abcam continued it’s trend of putting together unique and cutting edge events with the Crossing Boundaries: Lin...

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Chromatin: from Nucleosomes to Chromosomes

The Welcome Trust Chromatin meeting always draws a ton of interest from the EpiGenie crew, so we were anxious to see ...

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