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Stay on top of epigenetics, stem cell, and synthetic biology research with the latest headlines, special features, technology highlights, and conference action.

chromatin

Could Chromatin Organization be the Key to Eternal Youth?

For thousands of years great men such as Alexander the Great and Ponce de León have searched far and wide in their search for the fountain of youth and the hope of eternal life. But where they … [Read More...]

Stem Cell News

A TET-à-TET Between SIRT6 and 5hmC Controls Embryonic Stem Cell Fate

With many political parties fighting it out for influence in the UK general election last week, it is nice to see the spirit of cooperation alive and well in embryonic stem cells. In their latest … [Read More...]

dna-methylation

6mA Makes the Grade as a Eukaryotic Epigenetic Mark

There's no denying that we love DNA methylation, so we are delighted to learn of another form of DNA methylation that has come on the scene as an epigenetic mark. N6-Methyladenosine (6mA or … [Read More...]

dna-methylation

Twins Team up to Help Unravel DNA Methylation in Schizophrenia

While they can't see through lead or stop bullets with their chest, twins do have a superpower of their own - when it comes to unraveling the complex genomic and epigenomic changes underlying diseases … [Read More...]

dna-methylation

Upcycling the Epigenome in the Brain Help Neurons Stay in Touch

Upcycling is the latest of many green crazes where people keep hold of old furniture and instead of throwing it away, they repurpose it to give new life. It seems that the brain might be doing the … [Read More...]

SYNb

None Shall Pass! Genome Editing Stops Heritable Diseases in Their Tracks

The scientific world is still reeling from the news of the first genome editing of human embryos to treat genetic disease, as we have reported previously here on Epigenie. Unfortunately, the paper … [Read More...]

SYNb

Spray Your Way Free of Cystic Fibrosis with a Gene Editing Nasal Spray

With allergy season around the corner, you might be turning to nasal sprays to relieve the symptoms. But now Marie Egan's lab at Yale University have developed a very different type of nasal spray … [Read More...]

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chromatin

Could Chromatin Organization be the Key to Eternal Youth?

For thousands of years great men such as Alexander the Great and Ponce de León have searched far and wide in their search for the fountain of youth and the hope of eternal life. But where they … [Read More...]

Stem Cell News

A TET-à-TET Between SIRT6 and 5hmC Controls Embryonic Stem Cell Fate

With many political parties fighting it out for influence in the UK general election last week, it is nice to see the spirit of cooperation alive and well in embryonic stem cells. In their latest … [Read More...]

dna-methylation

Twins Team up to Help Unravel DNA Methylation in Schizophrenia

While they can't see through lead or stop bullets with their chest, twins do have a superpower of their own - when it comes to unraveling the complex genomic and epigenomic changes underlying diseases … [Read More...]

dna-methylation

Upcycling the Epigenome in the Brain Help Neurons Stay in Touch

Upcycling is the latest of many green crazes where people keep hold of old furniture and instead of throwing it away, they repurpose it to give new life. It seems that the brain might be doing the … [Read More...]

technology

Catching RNA Polymerases in Action: New NETs for Higher Resolution

For a long time RNA polymerases did not get the credit they actually deserve. They have been viewed as muscle-cars at a drag race: Waiting for a start signal to race along the gene only stopping for … [Read More...]

technology

UPCOMING WEBINAR: Locus-specific biochemical analysis of genome functions using enChIP: an application of CRISPR/Cas for purification of specific genomic regions

  Register Now Date: 8 June 2015 Time: 4pm PST/ 7pm EST Presenter: Hodaka Fujii, M.D., Ph.D.  Research Institute for Microbial Diseases, Osaka University Abstract Elucidation of … [Read More...]

non-coding-rna

Get in the Loop of Antisense Mediated Transcriptional Regulation

Long non-coding RNA research isn’t just a load of HOTAIR; since their initial discovery long non-coding RNAs have revealed their importance in regulating the genome. One such insight is the … [Read More...]

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SYNb

None Shall Pass! Genome Editing Stops Heritable Diseases in Their Tracks

The scientific world is still reeling from the news of the first genome editing of human embryos to treat genetic disease, as we have reported previously here on Epigenie. Unfortunately, the paper … [Read More...]

SYNb

Spray Your Way Free of Cystic Fibrosis with a Gene Editing Nasal Spray

With allergy season around the corner, you might be turning to nasal sprays to relieve the symptoms. But now Marie Egan's lab at Yale University have developed a very different type of nasal spray … [Read More...]

SYNb

Cas9 Gets an Illuminating Upgrade: Light-activatable Genome Editing

While dead Cas9 (dCas9) has been coupled to optogenetic systems to enable on the fly effector domain action, the not so dead Cas9 has just gotten a very different form of light induction that works … [Read More...]

SYNb

CRISPR-Cas9 Gene Editing of Human Embryos: A Look at the Science

Unless you were on Mars or in the middle of a Netflix binge, you couldn't have missed the paper that has been hitting the headlines all over the world this week - the first example of the genetic … [Read More...]

SYNb

CRISPR Goes Back to its Roots to Fight HIV

All the cool techniques people are developing with CRISPR-Cas9 are great and all, but sometimes a repurposed natural genetic system just has to go back to its roots. If CRISPR was originally a virus … [Read More...]

SYNb

Cancer Therapy Gets a Little Personal

Just like snowflakes we are all unique (at least genetically speaking), and unfortunately for modern medicine so are our cancers. This individuality in cancers, even of the same type or subtype, means … [Read More...]

SYNb

The Little Blue Pill Gets an Optogenetic Upgrade

While there's no denying that optogenetics is one stimulating piece of biotechnology, the double entendre of optogenetics being a 'turn on' has now become fact. The lab of Martin Fussenegger at ETH … [Read More...]

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chromatin

Could Chromatin Organization be the Key to Eternal Youth?

For thousands of years great men such as Alexander the Great and Ponce de León have searched far and wide in their search for the fountain of youth and the hope of eternal life. But where they … [Read More...]

Stem Cell News

A TET-à-TET Between SIRT6 and 5hmC Controls Embryonic Stem Cell Fate

With many political parties fighting it out for influence in the UK general election last week, it is nice to see the spirit of cooperation alive and well in embryonic stem cells. In their latest … [Read More...]

SYNb

CRISPR-Cas9 Gene Editing of Human Embryos: A Look at the Science

Unless you were on Mars or in the middle of a Netflix binge, you couldn't have missed the paper that has been hitting the headlines all over the world this week - the first example of the genetic … [Read More...]

Stem Cell News

Pioneering Transcription Factors Wiggle Towards Pluripotency

Canoes, camels, cars and catamarans have carried human pioneers far and wide; taking us to undiscovered lands to encounter unseen beauty, encouraged by the hope of fame, glory, and a lust for … [Read More...]

Stem Cell News

Human Preimplantation Embryos Go Retroviral

Our genomes are littered with tales of our evolutionary past, including infections from retroviruses that have left their mark in the vast expanses of the human genome. While most of the endogenous … [Read More...]

dna-methylation

The Differentiation Race: Not all Cells Move at the Same Speed

Christoph Bock discusses his recent paper 'Single-Cell DNA Methylome Sequencing and Bioinformatic Inference of Epigenomic Cell-State Dynamics' published in Cell Reports. Epigenetic Regulation of Cell … [Read More...]

Stem Cell News

Mass-tering the Stem Cell Reprogramming Process

Chaotic, uncoordinated, and seemingly without rhyme or reason…no, it’s not the daily stampede towards the barista for your first coffee of the day; rather it’s the words used to describe the early … [Read More...]

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EMBO Chromatin and Epigenetics 2015

Once more, the longstanding biennial EMBL meeting on Chromatin and Epigenetics in Heidelberg (Germany) draw together...

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Neuroepigenetics 2015

Researchers from the United States and around the world braved cancelations and layovers to finally find their way to...

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microRNAs Europe Meeting 2014

The microRNAs Europe Meeting is perhaps one of the best-kept secrets in the non coding RNA community. Similar to thos...

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Epigenomics of Common Diseases 2014

The 4th Wellcome Trust Epigenomics of Common Diseases conference in Cambridge brought together leading sci...

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Epigenetic plasticity: Implications in Neural (dys)function 2014

The latest EMBO workshop was held in ICVS in Braga on October 22-25th and focused on the state-of-the-art ...

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Chromatin and Epigenetics: From Omics to Single Cells

Abcam and co-organizers once again pulled off a delightful meeting – this time bridging two exciting approaches...

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World Congress of Psychiatric Genetics 2014

Copenhagen provided the scenic backdrop for this year’s World Congress of Psychiatric Genetics. About 883 participa...

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