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Stay on top of epigenetic's and non-coding RNA research with the latest headlines, special features, technology highlights, and conference action.

dna-methylation

Of Mice and Men: Human DNA Methylation Arrays for Both

Usually when you hear about translational research it involves taking findings from mice and applying them to humans. But Dr. Richard Saffery’s group from the University of Melbourne, apparently … [Read More...]

dna-methylation

Bullying and Epigenetics: Stick, Stones, and Epigenomes

Stress. We all know it’s not good for you. About a decade ago, Dr. Michael Meaney’s and Dr. Moshe Szyf’s research group from McGill University made some pioneering breakthroughs in the field … [Read More...]

non-coding-rna

The Future of lncRNAs with Dr. John Rinn

Dr. John L. Rinn from Harvard University and the Broad Institute (Harvard and MIT) is a prominent researcher in long non-coding RNAs (lncRNAs) and agreed to sit down and discuss his perspective on the … [Read More...]

dna-methylation

Dissolving the Layers in Genetics and Epigenetics with Dr. Adrian Bird

Dr. Adrian Bird discusses the dissolving barrier between genetics and epigenetics and why he's cautious about linking epigenetics in heredity.   Dissolving the Layers in Genetics and … [Read More...]

non-coding-rna

microRNAs Up Their Game: They Regulate Other microRNAs in the Heart

Just when you think you've got a handle on microRNAs, they go and up their game—regulating other microRNAs to produce large effects. To be accurate, they've been doing this all along, but now a … [Read More...]

non-coding-rna

Dynamic RNA Methylation Emerges as New Player in the Epigenetic Landscape

Methylation is a hot topic in the field of epigenetics whether it’s occurring on the cytosines of DNA or its histone protein friends. With a relatively well-known set of enzymes, methylation marks … [Read More...]

chromatin

SCANning Single Molecules to Pinpoint Co-Occurrence of Epigenetic Marks

Just because two people live on the same street doesn’t necessarily mean they live that close to each other or in the same house, yet that’s what you often have to assume when using ChIP to detect … [Read More...]

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dna-methylation

Epigenetics of Cancer Timeline

Epigenetic mechanisms have been studied in cancer for decades. Unfortunately, we haven't been around that long, but check out these great articles that capture the recent history of epigenetic … [Read More...]

non-coding-rna

The Rise of lncRNAs Timeline

Long non-coding RNAs, also known as lncRNAs, are gaining a truck load of momentum in the field of the epigenetics. Here we highlight the hottest research, methods papers, and the occasional interview … [Read More...]

dna-methylation

Epigenetics in Stem Cells Timeline

Epigenetics and stem cells go hand in pipette. These two research areas have seen explosive growth so we thought we'd highlight some of our favorite highlights. … [Read More...]

non-coding-rna

The Future of lncRNAs with Dr. John Rinn

Dr. John L. Rinn from Harvard University and the Broad Institute (Harvard and MIT) is a prominent researcher in long non-coding RNAs (lncRNAs) and agreed to sit down and discuss his perspective on the … [Read More...]

chromatin

Looking Under the Hood of Gene Regulation with Dr. Steven Henikoff

Dr. Henikoff discusses the next phase in gene regulation research, establishing causality in the gene expression flow and who the key players are.   Looking Under the Hood of Gene … [Read More...]

dna-methylation

Epigenetic Mechanisms in Autism

Autism spectrum disorder (ASD) refers to related neurodevelopmental disorders characterized by deficits in reciprocal communication and social interactions, coupled with restricted and repetitive … [Read More...]

dna-methylation

Guide: Getting Started with Genome-Wide 5-mC and 5-hmC Sequencing

With recent advances in sample preparation, highthroughput sequencing, and bioinformatics, researchers looking to study DNA methylation and hydroxymethylation now have several options for … [Read More...]

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dna-methylation

Of Mice and Men: Human DNA Methylation Arrays for Both

Usually when you hear about translational research it involves taking findings from mice and applying them to humans. But Dr. Richard Saffery’s group from the University of Melbourne, apparently … [Read More...]

chromatin

SCANning Single Molecules to Pinpoint Co-Occurrence of Epigenetic Marks

Just because two people live on the same street doesn’t necessarily mean they live that close to each other or in the same house, yet that’s what you often have to assume when using ChIP to detect … [Read More...]

technology

Genome Editing with the CRISPR/Cas System in Zebrafish

CRISPR/Cas is getting a lot of attention lately as a way to insert or delete genomic sequences in mammalian cells, but what about in model organisms? A new paper now shows that it works well in … [Read More...]

dna-methylation

MethylEdge™: Bisulfite Conversion without Fragmentation

Bisulfite conversion kits for DNA methylation studies are notorious for causing high levels of sample DNA fragmentation. What a pain. You may as well be flushing a portion of your hard-won samples … [Read More...]

dna-methylation

HpaII and MspI Strike Again in 5hmC Sequencing with HMST-Seq

It’s hard to tell some things apart—for instance, with her new haircut, Miley Cyrus could almost be mistaken for Pink. Well, almost. Anyhow, if you’re trying to tell 5-methylcytosines (5-mCs) … [Read More...]

non-coding-rna

Engineering (Epi)Genomes with CRISPR-Cas

To really figure out what genes really do, you gotta get in there and get your hands dirty. That usually means deleting or modifying genes, or other regulatory regions. In a recent “Research … [Read More...]

chromatin

Guide: Peak Calling for ChIP-Seq

Chromatin-immunoprecipitation sequencing (ChIP-seq) is the most widely used technique for analyzing Protein:DNA interactions. Very briefly, cells are cross-linked, fragmented and immunoprecipitated … [Read More...]

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Non-Coding RNA, Epigenetics and Transgenerational Inheritance

The latest conference of Abcam took place in Churchill College in Cambridge on April 11-12th. The differen...

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NCI Symposium on Chromosome Biology: Epigenetics in Development

The National Cancer Institute (NCI) Symposium on Chromosome Biology:  Epige...

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Epigenetic Marks and Cancer Drugs 2013

Over 350 scientists from 22 countries gathered in the USA oldest capital city, Santa Fe in New Mexico on March 2013, ...

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Epigenetics & Chromatin: Interactions and Processes 2013

As the march 14th issue of Cell celebrates the dynamic nucleus, there could not have been a bette...

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Noncoding RNAs in Development and Cancer 2013

The meeting's focus was equally divided between miRNAs and other non-coding RNAs , which was also reflected in the op...

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4th World Epigenetics Summit 2012

This was an overall excellent meeting with a fruitful mix of participants from industry and academia. It consisted of...

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Epigenetics and Stem Cells 2012

The latest Abcam Epigenetics and Stem Cells conference of took place in Robinson College in Cambridge, UK on October ...

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